Group Prof. Carreira

Group Carreira

The research program is focussed on four interrelated areas of organic synthesis: catalysis, methodology, natural products synthesis, medicinal and bioorganic chemistry.  Drawing from the areas of organometallic and coordination chemistry, as well as molecular recognition, the group is developing novel catalytic and stoichiometric reagents for chemical synthesis.  The identification of unusual chemical reactivity is given particular focus as the foundation for the development of practical, convenient, catalytic processes that permit access to new building blocks and define tactics for chemical synthesis.  The crafting of innovative strategies for the synthesis of natural products and their successful realization in the laboratory not only provides opportunities in which to showcase the methods discovered within the group, but also it affords a platform on which to explore the limits of reaction methods.  The research interests include the synthesis and study of small molecule modulators of pharmacokinetic properties in drug discovery.  Additionally, we are employing the tools of chemical synthesis to study the biological mode of action of a number of diverse, complex natural products.  Carreira has authored 165 research publications and holds 20 patents.